The innermost layer of the uterus is the endometrium. It thickens following the ovulation. After fertilization, it also creates an optimal environment for the developing embryo. Endometrial receptivity is the state at which the endometrium is ready for embryo implantation to take place. The ERA is a genetic diagnostic test used to assess the receptivity of the endometrium and its ability to obtain a successful embryo implant. ERA indicates the window of implantation (WOI), increasing your chances of successful transfer.
In IVF treatment, your physician would detect the endometrial ‘receptivity’ or ‘non-receptivity’ before implanting an embryo. The analysis reveals the timing of the implantation window and leads to a personalized embryo transfer (pET) timing based on the individual results obtained.
This test is recommended for patients with the apparently normal uterus and with normal endometrial thickness (≤6mm), in which no problems are apparent and still repeated IVF /ICSI cycles have failed.
Preimplantation genetic diagnosis (PGD) allows those with an inheritable condition in their family to avoid passing it on to their children. It involves checking the genes and/or chromosomes of embryos created through IVF.
Preimplantation genetic screening (PGS) involves checking the chromosomes of embryos conceived by ICSI for common abnormalities. Chromosomal abnormalities are a major cause of the failure of embryos to implant, and of miscarriages. They can also cause conditions such as Down’s syndrome. PGD can be used to test for virtually any genetic condition where a specific gene is known to cause that condition.
These tests may help identify the problems that are causing infertility. Once diagnosed, the problems can be treated by our doctors.